Oman Pharmaceutical Products Co. L.L.C.

Facility Overview

Capacity & Capabilities

Non Antibiotic Unit

Antibiotic Unit

Hormones Module

This is a segregated facility for the manufacture of the formulations containing ß-Lactam and Cephalosporin Antibiotics. The Block is isolated from other manufacturing facilities and all movements of personnel and materials from and into the Block are restricted. All necessary precautions are taken to ensure that the product is contained with the manufacturing sections. The pressure differentials are maintained for eliminating any scope for the cross contamination into any other sections. Personnel are subjected to periodical medical check up so as to detect any sensitivity problem.

Cephalosporin Tablets :

The facilities have been designed to manufacture tablets of different types such as,

Uncoated tablets
Film coated tablet

The department is organized and equipped with the relevant machines and equipments to facilitate following operations.

Granulation : The department is equipped to carry out Wet Granulation Process as well as the Dry Granulation process based on Roll Compactor. The granulation section is equipped with the HSMG, FBD and Vacuum Transfer System for conveying of the granules and the powders.

Blending : Granules are blended using the blender.

Compression : The compression machine CTX- 32. This machine has Pre-compression facility and has rated capacity of 70 RPM. The compression machine is provided with computerised on-line weight checking arrangement with SCADA terminal, which monitors the weight of the tablets and sets an alarm in case of any deviations from the preset limits. Tablets are passed through Metal Detector to confirm absence of metallic contamination.

Coating : The auto-coater is fully automatic coating system and the coating process is controlled by the PLC based process control system.

Packing : Blister pack machine (MC) is a Flat Bed type machine and can handle variety of the packing materials such as PVC, PVC/PVDC, or Aclar films. The machine is equipped with the Non- fill detector device for the detection of the empty blisters. The machine can be modified for Alu-Alu packing. The blister packing machine is connected to the automatic cartonating machine (PMM), which is fitted with the Pharma Code Bar Reader for On-Line identification of the packing materials.

Capacity : 300 million tablets per annum.

Cephalosporin Capsule :

The department is designed for processing Hard Gelatin Capsules. Powder / granules conveying is done using the Vacuum Transfer System to minimize the dust generation. Capsule filling machine (Model AF 90 T- capacity 90,000 capsules per hour) works on tamping principle. Filled capsules are checked with Metal Detectors to confirm absence of the metallic contamination. Machine is also equipped with the on-line weight checking system, which monitors and records the weights of the capsules on statistical sampling basis.

Packing : Filled capsules are packed using the blister pack machine (MC) & cartonating machine (HV1).

Capacity : 144 million capsules per annum.

Cephalosporin Dry Syrup :

Department is designed for processing of the Dry Syrup preparations. The Product is blended using the blender.

Filling & Packing : Bottles are cleaned with the help of dry and filtered compressed air with simultaneous application of the vacuum. Product is filled in the bottles using Monoblock dosing and capping and dose measure cup fitting machine. Filled bottles are weighed using On-line weighing Machine for monitoring the filled quantity. The bottles are then labeled using Pressure sensitive labels and packed in cartons using the cartonating machine described above and are then packed into the shippers with the help of Automatic Case packer machine.

Capacity : 7.2 million bottles per annum.